In some cases the Cls method fails to correctly refresh other child controls on the form. If you find that a Cls method on the form affects other controls on the form you should refresh those controls manually after the Cls method, or use the RefreshChildControls method that the VB6Form class exposes (starting with version 1.32):
Me.Cls()
Me.RefreshChildControls(False)
The argument is optional: if True all the controls on the form are refreshed, including nested controls. If False or omitted, only the controls that are contained directly on the form are refreshed.